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Identification of Topological Network Modules in Perturbed Protein Interaction Networks

Biological networks consist of functional modules, however detecting and characterizing such modules in networks remains challenging. Perturbing networks is one strategy for identifying modules. Here we used an advanced mathematical approach named topological data analysis (TDA) to interrogate two p...

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Publicat a:Sci Rep
Autors principals: Sardiu, Mihaela E., Gilmore, Joshua M., Groppe, Brad, Florens, Laurence, Washburn, Michael P.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5341041/
https://ncbi.nlm.nih.gov/pubmed/28272416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43845
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