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Identification of Topological Network Modules in Perturbed Protein Interaction Networks

Biological networks consist of functional modules, however detecting and characterizing such modules in networks remains challenging. Perturbing networks is one strategy for identifying modules. Here we used an advanced mathematical approach named topological data analysis (TDA) to interrogate two p...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Sardiu, Mihaela E., Gilmore, Joshua M., Groppe, Brad, Florens, Laurence, Washburn, Michael P.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5341041/
https://ncbi.nlm.nih.gov/pubmed/28272416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43845
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