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Identification of Topological Network Modules in Perturbed Protein Interaction Networks

Biological networks consist of functional modules, however detecting and characterizing such modules in networks remains challenging. Perturbing networks is one strategy for identifying modules. Here we used an advanced mathematical approach named topological data analysis (TDA) to interrogate two p...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Sardiu, Mihaela E., Gilmore, Joshua M., Groppe, Brad, Florens, Laurence, Washburn, Michael P.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5341041/
https://ncbi.nlm.nih.gov/pubmed/28272416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43845
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