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Involvement of Conserved Amino Acids in the C-Terminal Region of LINE-1 ORF2p in Retrotransposition

Long interspersed element 1 (L1) is the only currently active autonomous retroelement in the human genome. Along with the parasitic SVA and short interspersed element Alu, L1 is the source of DNA damage induced by retrotransposition: a copy-and-paste process that has the potential to disrupt gene fu...

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Publicado en:Genetics
Main Authors: Christian, Claiborne M., Sokolowski, Mark, deHaro, Dawn, Kines, Kristine J., Belancio, Victoria P.
Formato: Artigo
Idioma:Inglês
Publicado: Genetics Society of America 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5340329/
https://ncbi.nlm.nih.gov/pubmed/28100588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.116.191403
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