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Identification of L1 ORF2p sequence important to retrotransposition using Bipartile Alu retrotransposition (BAR)
Long Interspersed Element 1 (LINE-1 or L1) is capable of causing genomic instability through the activity of the L1 ORF2 protein (ORF2p). This protein contains endonuclease (EN) and reverse transcriptase (RT) domains that are necessary for the retrotransposition of L1 and the Short Interspersed Elem...
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| Pubblicato in: | Nucleic Acids Res |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4889948/ https://ncbi.nlm.nih.gov/pubmed/27095191 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw277 |
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