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Identification of L1 ORF2p sequence important to retrotransposition using Bipartile Alu retrotransposition (BAR)

Long Interspersed Element 1 (LINE-1 or L1) is capable of causing genomic instability through the activity of the L1 ORF2 protein (ORF2p). This protein contains endonuclease (EN) and reverse transcriptase (RT) domains that are necessary for the retrotransposition of L1 and the Short Interspersed Elem...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Main Authors: Christian, Claiborne M., deHaro, Dawn, Kines, Kristine J., Sokolowski, Mark, Belancio, Victoria P.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4889948/
https://ncbi.nlm.nih.gov/pubmed/27095191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw277
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