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Long Interspersed Element Sequencing (L1-Seq): A Method to Identify Somatic LINE-1 Insertions in the Human Genome

L1-seq is a high-throughput sequencing technique which is utilized to identify novel L1 insertions in genomic DNA samples of interest. Using special diagnostic nucleotides unique to the youngest and most active L1 sequence, we can amplify new somatic insertions. This technique has helped to establis...

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Detalhes bibliográficos
Publicado no:Methods Mol Biol
Main Authors: Doucet, Tara T., Kazazian, Haig H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5340310/
https://ncbi.nlm.nih.gov/pubmed/26895047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-3372-3_5
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