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Many LINE1 elements contribute to the transcriptome of human somatic cells

BACKGROUND: While LINE1 (L1) retroelements comprise nearly 20% of the human genome, the majority are thought to have been rendered transcriptionally inactive, due to either mutation or epigenetic suppression. How many L1 elements 'escape' these forms of repression and contribute to the tra...

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Detalhes bibliográficos
Main Authors: Rangwala, Sanjida H, Zhang, Lili, Kazazian, Haig H
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2768975/
https://ncbi.nlm.nih.gov/pubmed/19772661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2009-10-9-r100
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