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The L1 retrotransposition assay: A retrospective and toolkit

LINE1s (L1s) are a class of mammalian non-LTR (long terminal repeat) retroelements that make up nearly 20% of the human genome. Because of the difficulty of studying the mobilization of endogenous L1s, an exogenous cell culture retrotransposition assay has become integral to research in L1 biology....

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Rangwala, Sanjida H., Kazazian, Haig H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2763987/
https://ncbi.nlm.nih.gov/pubmed/19398011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2009.04.012
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