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Somatically acquired LINE-1 insertions in normal esophagus undergo clonal expansion in esophageal squamous cell carcinoma

Squamous cell carcinoma of the esophagus (SCC) is the most common form of esophageal cancer in the world and is typically diagnosed at an advanced stage when successful treatment is challenging. Understanding the mutational profile of this cancer may identify new treatment strategies. Because somati...

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Publicat a:Hum Mutat
Autors principals: Doucet-O’Hare, Tara T., Sharmad, Reema, Rodić, Nemanja, Anders, Robert A., Burns, Kathleen H., Kazazian, Haig H.
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5548391/
https://ncbi.nlm.nih.gov/pubmed/27319353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/humu.23027
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