Switching between Exonucleolysis and Replication by T7 DNA Polymerase Ensures High Fidelity

DNA polymerase catalyzes the accurate transfer of genetic information from one generation to the next, and thus it is vitally important for replication to be faithful. DNA polymerase fulfills the strict requirements for fidelity by a combination of mechanisms: 1) high selectivity for correct nucleot...

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Bibliografski detalji
Izdano u:Biophys J
Glavni autori: Hoekstra, Tjalle P., Depken, Martin, Lin, Szu-Ning, Cabanas-Danés, Jordi, Gross, Peter, Dame, Remus T., Peterman, Erwin J.G., Wuite, Gijs J.L.
Format: Artigo
Jezik:Inglês
Izdano: The Biophysical Society 2017
Teme:
Nucleic Acids and Genome Biophysics
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5340169/
https://ncbi.nlm.nih.gov/pubmed/28256218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.12.044
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