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c-Jun N-Terminal Protein Kinase 1 (JNK1), but Not JNK2, Is Essential for Tumor Necrosis Factor Alpha-Induced c-Jun Kinase Activation and Apoptosis

Two ubiquitously expressed isoforms of c-Jun N-terminal protein kinase (JNK), JNK1 and JNK2, have shared functions and different functions. However, the molecular mechanism is unknown. Here we report that JNK1, but not JNK2, is essential for tumor necrosis factor alpha (TNF-α)-induced c-Jun kinase a...

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Main Authors: Liu, Jing, Minemoto, Yuzuru, Lin, Anning
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2004
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC533995/
https://ncbi.nlm.nih.gov/pubmed/15572687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.24.10844-10856.2004
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