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Synergistic Interaction of MEK Kinase 2, c-Jun N-Terminal Kinase (JNK) Kinase 2, and JNK1 Results in Efficient and Specific JNK1 Activation

Mitogen-activated protein kinases (MAPKs) are activated through cascades or modules consisting of a MAPK, a MAPK kinase (MAPKK), and a MAPKK kinase (MAPKKK). Investigating the molecular basis of activation of the c-Jun N-terminal kinase (JNK) subgroup of MAPK by the MAPKKK MEKK2, we found that stron...

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Détails bibliographiques
Auteurs principaux: Cheng, Jinke, Yang, Jianhua, Xia, Ying, Karin, Michael, Su, Bing
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2000
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC85399/
https://ncbi.nlm.nih.gov/pubmed/10713157
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