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5-Fluorouracil Enhances Exosome-Dependent Accumulation of Polyadenylated rRNAs

The antimetabolite 5-fluorouracil (5FU) is a widely used chemotherapeutic for the treatment of solid tumors. Although 5FU slows DNA synthesis by inhibiting the ability of thymidylate synthetase to produce dTMP, the drug also has significant effects on RNA metabolism. Recent genome-wide assays for 5F...

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Detaylı Bibliyografya
Asıl Yazarlar: Fang, Feng, Hoskins, Jason, Butler, J. Scott
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2004
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC533989/
https://ncbi.nlm.nih.gov/pubmed/15572680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.24.10766-10776.2004
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