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5-Fluorouracil Enhances Exosome-Dependent Accumulation of Polyadenylated rRNAs

The antimetabolite 5-fluorouracil (5FU) is a widely used chemotherapeutic for the treatment of solid tumors. Although 5FU slows DNA synthesis by inhibiting the ability of thymidylate synthetase to produce dTMP, the drug also has significant effects on RNA metabolism. Recent genome-wide assays for 5F...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Fang, Feng, Hoskins, Jason, Butler, J. Scott
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2004
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC533989/
https://ncbi.nlm.nih.gov/pubmed/15572680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.24.10766-10776.2004
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