Mitochondrial PKM2 regulates oxidative stress-induced apoptosis by stabilizing Bcl2

Pyruvate kinase M2 isoform (PKM2) catalyzes the last step of glycolysis and plays an important role in tumor cell proliferation. Recent studies have reported that PKM2 also regulates apoptosis. However, the mechanisms underlying such a role of PKM2 remain elusive. Here we show that PKM2 translocates...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Cell Res
Main Authors: Liang, Ji, Cao, Ruixiu, Wang, Xiongjun, Zhang, Yajuan, Wang, Pan, Gao, Hong, Li, Chen, Yang, Fan, Zeng, Rong, Wei, Ping, Li, Dawei, Li, Wenfeng, Yang, Weiwei
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2017
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5339831/
https://ncbi.nlm.nih.gov/pubmed/28035139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2016.159
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker