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Mitochondrial PKM2 regulates oxidative stress-induced apoptosis by stabilizing Bcl2
Pyruvate kinase M2 isoform (PKM2) catalyzes the last step of glycolysis and plays an important role in tumor cell proliferation. Recent studies have reported that PKM2 also regulates apoptosis. However, the mechanisms underlying such a role of PKM2 remain elusive. Here we show that PKM2 translocates...
שמור ב:
| הוצא לאור ב: | Cell Res |
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| Main Authors: | , , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Nature Publishing Group
2017
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5339831/ https://ncbi.nlm.nih.gov/pubmed/28035139 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2016.159 |
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