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A missense mutation in zbtb17 blocks the earliest steps of T cell differentiation in zebrafish

T cells are an evolutionarily conserved feature of the adaptive immune systems of vertebrates. Comparative studies using evolutionarily distant species hold great promise for unraveling the genetic landscape underlying this process. To this end, we used ENU mutagenesis to generate mutant zebrafish w...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Lawir, Divine-Fondzenyuy, Iwanami, Norimasa, Schorpp, Michael, Boehm, Thomas
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5339814/
https://ncbi.nlm.nih.gov/pubmed/28266617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep44145
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