Polymorphisms and Pharmacogenomics for the Clinical Efficacy of Methotrexate in Patients with Rheumatoid Arthritis: A Systematic Review and Meta-analysis

Methotrexate (MTX) is widely used and considered a first-line disease modifying anti-rheumatic drug (DMARD) for the treatment of rheumatoid arthritis (RA). Many of the relevant genes have been investigated to estimate the association between gene polymorphisms and MTX effectiveness in RA patients, a...

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Udgivet i:Sci Rep
Main Authors: Qiu, Qi, Huang, Jing, Shu, Xiaoming, Fan, Huizheng, Zhou, Youwen, Xiao, Cheng
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5339794/
https://ncbi.nlm.nih.gov/pubmed/28266606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep44015
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