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Pharmacogenomics of Methotrexate Membrane Transport Pathway: Can Clinical Response to Methotrexate in Rheumatoid Arthritis Be Predicted?

Background: Methotrexate (MTX) is widely used for rheumatoid arthritis (RA) treatment. Single nucleotide polymorphisms (SNPs) could be used as predictors of patients’ therapeutic outcome variability. Therefore, this study aims to evaluate the influence of SNPs in genes encoding for MTX membrane tran...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Lima, Aurea, Bernardes, Miguel, Azevedo, Rita, Medeiros, Rui, Seabra, Vitor
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4490522/
https://ncbi.nlm.nih.gov/pubmed/26086825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms160613760
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