Prediction of Methotrexate Clinical Response in Portuguese Rheumatoid Arthritis Patients: Implication of MTHFR rs1801133 and ATIC rs4673993 Polymorphisms

Objective. Methotrexate (MTX), the most used drug in rheumatoid arthritis (RA) treatment, showing variability in clinical response, is often associated with genetic polymorphisms. This study aimed to elucidate the role of methylenetetrahydrofolate reductase (MTHFR) C677T and aminoimidazole carboxami...

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Detalhes bibliográficos
Main Authors: Lima, Aurea, Monteiro, Joaquim, Bernardes, Miguel, Sousa, Hugo, Azevedo, Rita, Seabra, Vitor, Medeiros, Rui
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4055378/
https://ncbi.nlm.nih.gov/pubmed/24967362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/368681
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