Genetic Polymorphisms of TYMS, MTHFR, ATIC, MTR, and MTRR Are Related to the Outcome of Methotrexate Therapy for Rheumatoid Arthritis in a Chinese Population

Objective: Analysis of the relationship between single nucleotide polymorphisms (SNPs) and outcomes of methotrexate (MTX) therapy for rheumatoid arthritis (RA) in China. Materials and Methods: TYMS 28 bp VNTR (rs34743033), MTHFR [677C>T (rs1801133) and 1298A>C (rs1801131)], ATIC 347C>G (rs2...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Lv, Shuang, Fan, HuiZhen, Li, Jiang, Yang, Hui, Huang, Jing, Shu, XiaoMing, Zhang, Lu, Xu, Yuan, Li, Xiaoya, Zuo, Jieyu, Xiao, Cheng
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6279856/
https://ncbi.nlm.nih.gov/pubmed/30546311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.01390
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