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Methotrexate for treating rheumatoid arthritis
BACKGROUND: Methotrexate is a folic acid antagonist widely used for the treatment of neoplastic disorders. Methotrexate inhibits the synthesis of deoxyribonucleic acid (DNA), ribonucleic acid (RNA) and proteins by binding to dihydrofolate reductase. Currently, methotrexate is among the most commonly...
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| Udgivet i: | Cochrane Database Syst Rev |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
John Wiley & Sons, Ltd
2014
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| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7047041/ https://ncbi.nlm.nih.gov/pubmed/24916606 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/14651858.CD000957.pub2 |
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