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Methotrexate for treating rheumatoid arthritis
BACKGROUND: Methotrexate is a folic acid antagonist widely used for the treatment of neoplastic disorders. Methotrexate inhibits the synthesis of deoxyribonucleic acid (DNA), ribonucleic acid (RNA) and proteins by binding to dihydrofolate reductase. Currently, methotrexate is among the most commonly...
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| Publicado no: | Cochrane Database Syst Rev |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley & Sons, Ltd
2014
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7047041/ https://ncbi.nlm.nih.gov/pubmed/24916606 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/14651858.CD000957.pub2 |
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