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Polymorphisms and Pharmacogenomics for the Clinical Efficacy of Methotrexate in Patients with Rheumatoid Arthritis: A Systematic Review and Meta-analysis

Methotrexate (MTX) is widely used and considered a first-line disease modifying anti-rheumatic drug (DMARD) for the treatment of rheumatoid arthritis (RA). Many of the relevant genes have been investigated to estimate the association between gene polymorphisms and MTX effectiveness in RA patients, a...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Qiu, Qi, Huang, Jing, Shu, Xiaoming, Fan, Huizheng, Zhou, Youwen, Xiao, Cheng
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5339794/
https://ncbi.nlm.nih.gov/pubmed/28266606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep44015
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