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Dissecting the Molecular Pathway Involved in PLK2 Kinase-mediated α-Synuclein-selective Autophagic Degradation

Increasing lines of evidence support the causal link between α-synuclein (α-syn) accumulation in the brain and Parkinson's disease (PD) pathogenesis. Therefore, lowering α-syn protein levels may represent a viable therapeutic strategy for the treatment of PD and related disorders. We recently d...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Dahmene, Manel, Bérard, Morgan, Oueslati, Abid
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5339772/
https://ncbi.nlm.nih.gov/pubmed/28154193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.759373
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