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Lysosomal Degradation of α-Synuclein in Vivo

Pathologic accumulation of α-synuclein is a feature of human parkinsonism and other neurodegenerative diseases. This accumulation may be counteracted by mechanisms of protein degradation that have been investigated in vitro but remain to be elucidated in animal models. In this study, lysosomal clear...

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Bibliografski detalji
Glavni autori: Mak, Sally K., McCormack, Alison L., Manning-Boğ, Amy B., Cuervo, Ana Maria, Di Monte, Donato A.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2859524/
https://ncbi.nlm.nih.gov/pubmed/20200163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.074617
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