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Lysosomal Degradation of α-Synuclein in Vivo
Pathologic accumulation of α-synuclein is a feature of human parkinsonism and other neurodegenerative diseases. This accumulation may be counteracted by mechanisms of protein degradation that have been investigated in vitro but remain to be elucidated in animal models. In this study, lysosomal clear...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2859524/ https://ncbi.nlm.nih.gov/pubmed/20200163 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.074617 |
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