Pathological Modifications of α-Synuclein in 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine (MPTP)-Treated Squirrel Monkeys

α-Synuclein expression is increased in dopaminergic neurons challenged by toxic insults. Here, we assessed whether this upregulation is accompanied by pathological accumulation of α-synuclein and protein modifications (i.e. nitration, phosphorylation and aggregation) that are typically observed in P...

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Detalhes bibliográficos
Main Authors: McCormack, Alison L., Mak, Sally K., Shenasa, Maryam, Langston, William J., Forno, Lysia S., Di Monte, Donato A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2745435/
https://ncbi.nlm.nih.gov/pubmed/18648323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/NEN.0b013e318180f0bd
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