Skap2 is required for β(2) integrin–mediated neutrophil recruitment and functions

Integrin activation is required for neutrophil functions. Impaired integrin activation on neutrophils is the hallmark of leukocyte adhesion deficiency (LAD) syndrome in humans, characterized by impaired leukocyte recruitment and recurrent infections. The Src kinase–associated phosphoprotein 2 (Skap2...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Exp Med
Main Authors: Boras, Mark, Volmering, Stephanie, Bokemeyer, Arne, Rossaint, Jan, Block, Helena, Bardel, Bernadette, Van Marck, Veerle, Heitplatz, Barbara, Kliche, Stefanie, Reinhold, Annegret, Lowell, Clifford, Zarbock, Alexander
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2017
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5339670/
https://ncbi.nlm.nih.gov/pubmed/28183734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20160647
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