Skap2 is required for β(2) integrin–mediated neutrophil recruitment and functions

Integrin activation is required for neutrophil functions. Impaired integrin activation on neutrophils is the hallmark of leukocyte adhesion deficiency (LAD) syndrome in humans, characterized by impaired leukocyte recruitment and recurrent infections. The Src kinase–associated phosphoprotein 2 (Skap2...

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Udgivet i:J Exp Med
Main Authors: Boras, Mark, Volmering, Stephanie, Bokemeyer, Arne, Rossaint, Jan, Block, Helena, Bardel, Bernadette, Van Marck, Veerle, Heitplatz, Barbara, Kliche, Stefanie, Reinhold, Annegret, Lowell, Clifford, Zarbock, Alexander
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2017
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Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5339670/
https://ncbi.nlm.nih.gov/pubmed/28183734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20160647
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