Skap2 is required for β(2) integrin–mediated neutrophil recruitment and functions

Integrin activation is required for neutrophil functions. Impaired integrin activation on neutrophils is the hallmark of leukocyte adhesion deficiency (LAD) syndrome in humans, characterized by impaired leukocyte recruitment and recurrent infections. The Src kinase–associated phosphoprotein 2 (Skap2...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Exp Med
Auteurs principaux: Boras, Mark, Volmering, Stephanie, Bokemeyer, Arne, Rossaint, Jan, Block, Helena, Bardel, Bernadette, Van Marck, Veerle, Heitplatz, Barbara, Kliche, Stefanie, Reinhold, Annegret, Lowell, Clifford, Zarbock, Alexander
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 2017
Sujets:
Research Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5339670/
https://ncbi.nlm.nih.gov/pubmed/28183734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20160647
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