L-selectin shedding affects bacterial clearance in the lung: a new regulatory pathway for integrin outside-in signaling

Pneumonia induced by Gram-negative bacteria is a common and serious disease associated with high morbidity and mortality. Elimination of bacterial pathogens relies on the recruitment and functions of neutrophils. The adhesion molecule L-selectin has recently been implicated in integrin activation in...

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Udgivet i:Blood
Main Authors: Cappenberg, Anika, Margraf, Andreas, Thomas, Katharina, Bardel, Bernadette, McCreedy, Dylan A., Van Marck, Veerle, Mellmann, Alexander, Lowell, Clifford A., Zarbock, Alexander
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2019
Fag:
Phagocytes, Granulocytes, and Myelopoiesis
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6839956/
https://ncbi.nlm.nih.gov/pubmed/31366620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2019000685
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