L-selectin shedding affects bacterial clearance in the lung: a new regulatory pathway for integrin outside-in signaling

Pneumonia induced by Gram-negative bacteria is a common and serious disease associated with high morbidity and mortality. Elimination of bacterial pathogens relies on the recruitment and functions of neutrophils. The adhesion molecule L-selectin has recently been implicated in integrin activation in...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Cappenberg, Anika, Margraf, Andreas, Thomas, Katharina, Bardel, Bernadette, McCreedy, Dylan A., Van Marck, Veerle, Mellmann, Alexander, Lowell, Clifford A., Zarbock, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2019
Assuntos:
Phagocytes, Granulocytes, and Myelopoiesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6839956/
https://ncbi.nlm.nih.gov/pubmed/31366620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2019000685
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