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Rolling on E- or P-selectin induces the extended but not high-affinity conformation of LFA-1 in neutrophils

Human blood neutrophils rolling on E- or P-selectin reduced their rolling velocity when intercellular adhesion molecule (ICAM)–1 was available. Similar to mouse neutrophils, this was dependent on P-selectin glycoprotein ligand 1 (PSGL1), α(L)β(2) integrin, the Src family tyrosine kinase FGR and sple...

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Detalhes bibliográficos
Main Authors: Kuwano, Yoshihiro, Spelten, Oliver, Zhang, Hong, Ley, Klaus, Zarbock, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3324292/
https://ncbi.nlm.nih.gov/pubmed/20445017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-01-266122
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