Distinct roles for talin-1 and kindlin-3 in LFA-1 extension and affinity regulation

In inflammation, neutrophils and other leukocytes roll along the microvascular endothelium before arresting and transmigrating into inflamed tissues. Arrest requires conformational activation of the integrin lymphocyte function-associated antigen-1 (LFA-1). Mutations of the FERMT3 gene encoding kind...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Lefort, Craig T., Rossaint, Jan, Moser, Markus, Petrich, Brian G., Zarbock, Alexander, Monkley, Susan J., Critchley, David R., Ginsberg, Mark H., Fässler, Reinhard, Ley, Klaus
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2012
Matèries:
Phagocytes, Granulocytes, and Myelopoiesis
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3359742/
https://ncbi.nlm.nih.gov/pubmed/22431571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-08-373118
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars