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Detection of Imprinted Genes by Single-Cell Allele-Specific Gene Expression

Genomic imprinting results in parental-specific gene expression. Imprinted genes are involved in the etiology of rare syndromes and have been associated with common diseases such as diabetes and cancer. Standard RNA bulk cell sequencing applied to whole-tissue samples has been used to detect imprint...

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Detalhes bibliográficos
Publicado no:Am J Hum Genet
Main Authors: Santoni, Federico A., Stamoulis, Georgios, Garieri, Marco, Falconnet, Emilie, Ribaux, Pascale, Borel, Christelle, Antonarakis, Stylianos E.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5339288/
https://ncbi.nlm.nih.gov/pubmed/28190458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2017.01.028
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