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Frequent cases of RAS-mutated Down syndrome acute lymphoblastic leukaemia lack JAK2 mutations
Children with Down syndrome (DS) and acute lymphoblastic leukaemia (ALL) have poorer survival and more relapses, than non-DS children with ALL, highlighting an urgent need for deeper mechanistic understanding of DS-ALL. Here, using full exome or cancer genes-targeted sequencing of 42 ALL samples fro...
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| Yayımlandı: | Nat Commun |
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| Asıl Yazarlar: | , , , , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2014
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4665216/ https://ncbi.nlm.nih.gov/pubmed/25105841 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms5654 |
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