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Recombinant Infectious Bronchitis Coronavirus Beaudette with the Spike Protein Gene of the Pathogenic M41 Strain Remains Attenuated but Induces Protective Immunity

We have replaced the ectodomain of the spike (S) protein of the Beaudette strain (Beau-R; apathogenic for Gallus domesticus chickens) of avian infectious bronchitis coronavirus (IBV) with that from the pathogenic M41 strain to produce recombinant IBV BeauR-M41(S). We have previously shown that this...

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Bibliografiska uppgifter
Huvudupphovsmän: Hodgson, Teri, Casais, Rosa, Dove, Brian, Britton, Paul, Cavanagh, Dave
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2004
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC533908/
https://ncbi.nlm.nih.gov/pubmed/15564488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.24.13804-13811.2004
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