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Recombinant Infectious Bronchitis Coronavirus Beaudette with the Spike Protein Gene of the Pathogenic M41 Strain Remains Attenuated but Induces Protective Immunity

We have replaced the ectodomain of the spike (S) protein of the Beaudette strain (Beau-R; apathogenic for Gallus domesticus chickens) of avian infectious bronchitis coronavirus (IBV) with that from the pathogenic M41 strain to produce recombinant IBV BeauR-M41(S). We have previously shown that this...

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Autors principals: Hodgson, Teri, Casais, Rosa, Dove, Brian, Britton, Paul, Cavanagh, Dave
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC533908/
https://ncbi.nlm.nih.gov/pubmed/15564488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.24.13804-13811.2004
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