Recombinant Infectious Bronchitis Coronavirus Beaudette with the Spike Protein Gene of the Pathogenic M41 Strain Remains Attenuated but Induces Protective Immunity

We have replaced the ectodomain of the spike (S) protein of the Beaudette strain (Beau-R; apathogenic for Gallus domesticus chickens) of avian infectious bronchitis coronavirus (IBV) with that from the pathogenic M41 strain to produce recombinant IBV BeauR-M41(S). We have previously shown that this...

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Hlavní autoři: Hodgson, Teri, Casais, Rosa, Dove, Brian, Britton, Paul, Cavanagh, Dave
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2004
Témata:
Pathogenesis and Immunity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC533908/
https://ncbi.nlm.nih.gov/pubmed/15564488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.24.13804-13811.2004
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