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Recombinant Avian Infectious Bronchitis Virus Expressing a Heterologous Spike Gene Demonstrates that the Spike Protein Is a Determinant of Cell Tropism

A recombinant infectious bronchitis virus (IBV), BeauR-M41(S), was generated using our reverse genetics system (R. Casais, V. Thiel, S. G. Siddell, D. Cavanagh, and P. Britton, J. Virol. 75:12359-12369, 2001), in which the ectodomain region of the spike gene from IBV M41-CK replaced the correspondin...

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Detalhes bibliográficos
Main Authors: Casais, Rosa, Dove, Brian, Cavanagh, David, Britton, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC167237/
https://ncbi.nlm.nih.gov/pubmed/12885925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.16.9084-9089.2003
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