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Galectin-3 directs antimicrobial guanylate binding proteins to vacuoles furnished with bacterial secretion systems

Many invasive bacteria establish pathogen-containing vacuoles (PVs) as intracellular niches for microbial growth. Immunity to these infections is dependent on the ability of host cells to recognize PVs as targets for host defense. The delivery of several host defense proteins to PVs is controlled by...

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Foilsithe in:Proc Natl Acad Sci U S A
Main Authors: Feeley, Eric M., Pilla-Moffett, Danielle M., Zwack, Erin E., Piro, Anthony S., Finethy, Ryan, Kolb, Joseph P., Martinez, Jennifer, Brodsky, Igor E., Coers, Jörn
Formáid: Artigo
Teanga:Inglês
Foilsithe: National Academy of Sciences 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5338555/
https://ncbi.nlm.nih.gov/pubmed/28193861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1615771114
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