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Ubiquitin systems mark pathogen-containing vacuoles as targets for host defense by guanylate binding proteins
Many microbes create and maintain pathogen-containing vacuoles (PVs) as an intracellular niche permissive for microbial growth and survival. The destruction of PVs by IFNγ-inducible guanylate binding protein (GBP) and immunity-related GTPase (IRG) host proteins is central to a successful immune resp...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4611635/ https://ncbi.nlm.nih.gov/pubmed/26417105 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1515966112 |
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