Chlamydia trachomatis Is Resistant to Inclusion Ubiquitination and Associated Host Defense in Gamma Interferon-Primed Human Epithelial Cells

The cytokine gamma interferon (IFN-γ) induces cell-autonomous immunity to combat infections with intracellular pathogens, such as the bacterium Chlamydia trachomatis. The present study demonstrates that IFN-γ-primed human cells ubiquitinate and eliminate intracellular Chlamydia-containing vacuoles,...

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Veröffentlicht in:mBio
Hauptverfasser: Haldar, Arun K., Piro, Anthony S., Finethy, Ryan, Espenschied, Scott T., Brown, Hannah E., Giebel, Amanda M., Frickel, Eva-Maria, Nelson, David E., Coers, Jörn
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2016
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5156299/
https://ncbi.nlm.nih.gov/pubmed/27965446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01417-16
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