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Galectin-3 directs antimicrobial guanylate binding proteins to vacuoles furnished with bacterial secretion systems

Many invasive bacteria establish pathogen-containing vacuoles (PVs) as intracellular niches for microbial growth. Immunity to these infections is dependent on the ability of host cells to recognize PVs as targets for host defense. The delivery of several host defense proteins to PVs is controlled by...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Feeley, Eric M., Pilla-Moffett, Danielle M., Zwack, Erin E., Piro, Anthony S., Finethy, Ryan, Kolb, Joseph P., Martinez, Jennifer, Brodsky, Igor E., Coers, Jörn
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5338555/
https://ncbi.nlm.nih.gov/pubmed/28193861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1615771114
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