Ubiquitin systems mark pathogen-containing vacuoles as targets for host defense by guanylate binding proteins

Many microbes create and maintain pathogen-containing vacuoles (PVs) as an intracellular niche permissive for microbial growth and survival. The destruction of PVs by IFNγ-inducible guanylate binding protein (GBP) and immunity-related GTPase (IRG) host proteins is central to a successful immune resp...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Haldar, Arun K., Foltz, Clémence, Finethy, Ryan, Piro, Anthony S., Feeley, Eric M., Pilla-Moffett, Danielle M., Komatsu, Masaki, Frickel, Eva-Maria, Coers, Jörn
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2015
Fag:
PNAS Plus
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4611635/
https://ncbi.nlm.nih.gov/pubmed/26417105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1515966112
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