Interleukin 37 reverses the metabolic cost of inflammation, increases oxidative respiration, and improves exercise tolerance

IL-1 family member interleukin 37 (IL-37) has broad antiinflammatory properties and functions as a natural suppressor of innate inflammation. In this study, we demonstrate that treatment with recombinant human IL-37 reverses the decrease in exercise performance observed during systemic inflammation....

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Cavalli, Giulio, Justice, Jamie N., Boyle, Kristen E., D’Alessandro, Angelo, Eisenmesser, Elan Z., Herrera, Jonathan J., Hansen, Kirk C., Nemkov, Travis, Stienstra, Rinke, Garlanda, Cecilia, Mantovani, Alberto, Seals, Douglas R., Dagna, Lorenzo, Joosten, Leo A. B., Ballak, Dov B., Dinarello, Charles A.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2017
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5338542/
https://ncbi.nlm.nih.gov/pubmed/28193888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1619011114
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