Interleukin 37 reverses the metabolic cost of inflammation, increases oxidative respiration, and improves exercise tolerance

IL-1 family member interleukin 37 (IL-37) has broad antiinflammatory properties and functions as a natural suppressor of innate inflammation. In this study, we demonstrate that treatment with recombinant human IL-37 reverses the decrease in exercise performance observed during systemic inflammation....

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Enregistré dans:
Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Cavalli, Giulio, Justice, Jamie N., Boyle, Kristen E., D’Alessandro, Angelo, Eisenmesser, Elan Z., Herrera, Jonathan J., Hansen, Kirk C., Nemkov, Travis, Stienstra, Rinke, Garlanda, Cecilia, Mantovani, Alberto, Seals, Douglas R., Dagna, Lorenzo, Joosten, Leo A. B., Ballak, Dov B., Dinarello, Charles A.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2017
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5338542/
https://ncbi.nlm.nih.gov/pubmed/28193888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1619011114
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