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Treating experimental arthritis with the innate immune inhibitor interleukin-37 reduces joint and systemic inflammation
Objectives. The IL-1 family member IL-37 was recently characterized as a fundamental inhibitor of innate inflammation. We investigated the effects of recombinant IL-37 in joint inflammation and joint pathology in a mouse model of arthritis. In addition, we explored the potential for therapeutic use...
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| Publicado no: | Rheumatology (Oxford) |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5144668/ https://ncbi.nlm.nih.gov/pubmed/27567100 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/rheumatology/kew325 |
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