MicroRNA-10a is crucial for endothelial response to different flow patterns via interaction of retinoid acid receptors and histone deacetylases

Histone deacetylases (HDACs) and microRNAs (miRs) have emerged as two important epigenetic factors in the regulation of vascular physiology. This study aimed to elucidate the relationship between HDACs and miRs in the hemodynamic modulation of endothelial cell (EC) dysfunction. We found that miR-10a...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Lee, Ding-Yu, Lin, Ting-Er, Lee, Chih-I, Zhou, Jing, Huang, Yi-Hsuan, Lee, Pei-Ling, Shih, Yu-Tsung, Chien, Shu, Chiu, Jeng-Jiann
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5338411/
https://ncbi.nlm.nih.gov/pubmed/28167758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1621425114
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