MicroRNA-10a is crucial for endothelial response to different flow patterns via interaction of retinoid acid receptors and histone deacetylases

Histone deacetylases (HDACs) and microRNAs (miRs) have emerged as two important epigenetic factors in the regulation of vascular physiology. This study aimed to elucidate the relationship between HDACs and miRs in the hemodynamic modulation of endothelial cell (EC) dysfunction. We found that miR-10a...

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Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Lee, Ding-Yu, Lin, Ting-Er, Lee, Chih-I, Zhou, Jing, Huang, Yi-Hsuan, Lee, Pei-Ling, Shih, Yu-Tsung, Chien, Shu, Chiu, Jeng-Jiann
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2017
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5338411/
https://ncbi.nlm.nih.gov/pubmed/28167758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1621425114
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