MicroRNA-10a is crucial for endothelial response to different flow patterns via interaction of retinoid acid receptors and histone deacetylases

Histone deacetylases (HDACs) and microRNAs (miRs) have emerged as two important epigenetic factors in the regulation of vascular physiology. This study aimed to elucidate the relationship between HDACs and miRs in the hemodynamic modulation of endothelial cell (EC) dysfunction. We found that miR-10a...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Lee, Ding-Yu, Lin, Ting-Er, Lee, Chih-I, Zhou, Jing, Huang, Yi-Hsuan, Lee, Pei-Ling, Shih, Yu-Tsung, Chien, Shu, Chiu, Jeng-Jiann
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2017
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5338411/
https://ncbi.nlm.nih.gov/pubmed/28167758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1621425114
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